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Geroscience and Brain

Meaning

Geroscience and Brain is an interdisciplinary field that investigates the fundamental biological mechanisms of aging as they specifically relate to brain health, cognitive decline, and neurodegenerative disease. This approach posits that targeting the root causes of aging—such as cellular senescence, mitochondrial dysfunction, and chronic inflammation—can simultaneously prevent or mitigate multiple age-related brain pathologies. Clinicians utilize the principles of geroscience to develop longevity protocols aimed at extending “healthspan” for the brain, not just lifespan, by focusing on upstream biological drivers of neurological aging. This represents a paradigm shift from treating individual diseases to treating the aging process itself.