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Germline

Meaning

Germline refers to the cellular lineage that is passed down through successive generations, specifically encompassing the gametes (sperm and egg) and the cells that give rise to them. In the context of hormonal health and wellness, understanding germline genetics is critical as it dictates inherited susceptibilities to endocrine disorders, such as congenital adrenal hyperplasia or familial tendencies toward early menopause. These are the inherent biological blueprints that influence the programming of the entire endocrine system from conception onward. We recognize that these fixed elements interact with environmental and lifestyle factors throughout life.