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Genomic Effects of Hormones

Meaning

The Genomic Effects of Hormones refer to the mechanism by which steroid and thyroid hormones directly influence gene expression by binding to specific intracellular receptors, subsequently altering the rate of protein synthesis within the target cell. This is a slower but more profound and long-lasting mode of hormonal action, contrasting with rapid, non-genomic effects. These effects are central to long-term physiological changes, including sexual differentiation, metabolic programming, and tissue development throughout the lifespan. Understanding this pathway is essential for appreciating the deep biological impact of endocrine balance.