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Genomic Disparity

Meaning

Genomic Disparity refers to the unequal distribution of genomic features, such as specific mutations, gene expression profiles, or epigenetic modifications, across different populations defined by factors like race, ethnicity, or socioeconomic status. This concept highlights the variations in genetic and molecular landscapes of diseases, including hormone-sensitive cancers and endocrine disorders, among diverse groups. These differences can influence disease incidence, progression, and, critically, the response to targeted therapies, contributing to observed health inequalities. Addressing genomic disparity is a core objective of precision medicine to ensure equitable and effective clinical care for all individuals.