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Genome Integrity

Meaning

Genome Integrity is the state of having a complete, accurate, and stable genetic blueprint within every cell, which is essential for proper cellular function, hormonal signaling, and overall organismal health. This concept refers to the cell’s continuous, dynamic process of monitoring and repairing damage to its DNA, thereby preventing mutations and maintaining the fidelity of genetic information. The preservation of this integrity is a cornerstone of longevity, as accumulated genomic damage is a major driver of cellular senescence and age-related hormonal decline. Maintaining a robust repair system is crucial for endocrine resilience.