Question 1

What is the Meaning of Gengnianqi?

Accepted Answer

Gengnianqi refers to the physiological transition in women marking the permanent cessation of menstruation, signifying the end of reproductive capability. This natural biological phase typically occurs in middle age, characterized by ovarian follicular exhaustion and subsequent hormonal shifts.

Question 2

What is the Context of Gengnianqi?

Accepted Answer

This phenomenon occurs within the female endocrine system, specifically involving the ovaries' diminished function in producing primary sex hormones like estrogen and progesterone. The changes influence the hypothalamic-pituitary-gonadal axis, impacting systemic regulation and metabolic processes throughout the body.

Question 3

What is the Significance of Gengnianqi?

Accepted Answer

Gengnianqi holds substantial clinical importance due to its widespread systemic effects on women's health. It influences bone mineral density, cardiovascular risk, urogenital integrity, and cognitive function, necessitating careful medical consideration for symptom management and long-term health maintenance.

Question 4

What is the Mechanism of Gengnianqi?

Accepted Answer

The core mechanism involves the progressive depletion of ovarian follicles, leading to a significant decline in estradiol and inhibin production. This hormonal reduction removes the negative feedback on the pituitary gland, resulting in elevated levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), driving the characteristic endocrine profile.

Question 5

What is the Application of Gengnianqi?

Accepted Answer

Clinical practice addresses Gengnianqi through individualized management strategies, which may include lifestyle adjustments, non-hormonal interventions, or hormone therapy. These approaches aim to alleviate common symptoms such as vasomotor instability, sleep disturbances, and mood changes, supporting a woman's well-being during this transition.

Question 6

What is the Metric of Gengnianqi?

Accepted Answer

Diagnosis of Gengnianqi is primarily clinical, based on 12 consecutive months of amenorrhea in the absence of other physiological or pathological causes. Biochemical confirmation often involves measuring elevated serum FSH levels and decreased estradiol concentrations, providing objective indicators of ovarian insufficiency.

Question 7

What is the Risk of Gengnianqi?

Accepted Answer

While Gengnianqi is a natural process, it is associated with increased risks for certain health conditions, including osteoporosis, cardiovascular disease, and genitourinary syndrome of menopause. Management strategies, particularly hormone therapy, carry their own specific risks such as potential for venous thromboembolism or certain cancers, requiring thorough patient evaluation and monitoring.

Gengnianqi

Meaning

Context

Significance

Mechanism

Application

Metric

Risk

Can Lifestyle Changes Alone Prevent Significant Bone Density Loss after Menopause?

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