Skip to main content

Genetic Lipid Phenotype Identification

Meaning

Genetic Lipid Phenotype Identification is the diagnostic process of utilizing an individual’s genetic information to determine the inherited molecular basis for their specific pattern of dyslipidemia. This involves analyzing single nucleotide polymorphisms (SNPs) or mutations in genes that encode for key proteins involved in lipoprotein metabolism, such as ApoB, PCSK9, or the LDL receptor. Identifying the genetic phenotype, such as Familial Hypercholesterolemia or a polygenic risk score, provides crucial insight into the severity, trajectory, and optimal pharmacological response for a patient’s lipid disorder. This precision approach refines risk stratification.