What is the Origin of Genetic Data Informed Supplementation?

This practice is an application of the rapidly growing field of nutrigenomics. 'Genetic Data Informed' signifies the use of genomic information as the foundational evidence, and 'Supplementation' refers to the strategic use of exogenous compounds to support physiological function.

What is the Mechanism of Genetic Data Informed Supplementation?

Genetic variants, such as MTHFR polymorphisms or COMT variants, can reveal a diminished capacity for converting inactive nutrients into their active forms or clearing spent hormones. For instance, a person with a compromised MTHFR enzyme may require the bioactive form of folate, 5-MTHF, rather than folic acid. By providing the correct form or dose of a nutrient that directly supports a genetically compromised pathway, the intervention optimizes metabolic efficiency and restores biochemical balance.

Genetic Data Informed Supplementation ∞ Area

Genetic Data Informed Supplementation

Meaning

Genetic data informed supplementation is the practice of tailoring nutritional or hormonal supplement recommendations based on an individual’s specific genetic profile, particularly variants that affect nutrient absorption, metabolism, or utilization. This personalized approach aims to bypass genetic bottlenecks, compensate for reduced enzyme efficiency, or address heightened requirements indicated by the genotype. It represents a precise, data-driven evolution of traditional supplementation.