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Gene-Nutrient Interaction

Meaning

Gene-Nutrient Interaction, a core principle of nutrigenomics, describes the reciprocal relationship where an individual’s unique genetic profile influences how they metabolize, absorb, and utilize specific nutrients, and conversely, how those nutrients modulate gene expression. This intricate biological crosstalk is profoundly relevant to hormonal health, as genetic variations can affect enzyme activity crucial for hormone synthesis, metabolism, and detoxification. Understanding these interactions allows the clinical translator to move beyond generalized dietary advice to create truly personalized nutritional protocols that optimize specific endocrine pathways. The goal is to leverage diet to compensate for genetic vulnerabilities and enhance hormonal balance.