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Gene-Hormone Interaction

Meaning

Gene-Hormone Interaction is the complex, reciprocal biological relationship where an individual’s specific genetic makeup influences the synthesis, transport, receptor sensitivity, and metabolism of hormones, while simultaneously, hormones can modulate gene expression. This intricate interplay is the foundation of personalized hormonal health, explaining why two individuals may respond vastly differently to the same dose of a hormone or therapeutic agent. It dictates an individual’s unique endocrine landscape and disease susceptibility.