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Gene Expression Reprogramming

Meaning

Gene Expression Reprogramming is the profound process of altering the fundamental pattern of genes that are actively transcribed into functional products (RNA and protein) within a cell, thereby shifting the cell’s core functional state or identity. This mechanism moves beyond simple quantitative up or down-regulation to a wholesale, qualitative change in the cell’s transcriptional landscape, often in response to powerful external signals or therapeutic factors. In longevity science, this is the mechanism by which cells can potentially revert to a more youthful, resilient, or regenerative phenotype.