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GABAergic Neurotransmission

Meaning

The primary inhibitory signaling process within the central nervous system mediated by the neurotransmitter Gamma-Aminobutyric Acid (GABA), which acts by binding to specific GABA receptors on the postsynaptic neuron. This binding typically results in an influx of chloride ions, hyperpolarizing the neuron and making it less likely to fire an action potential. This inhibitory action is crucial for regulating neuronal excitability, promoting relaxation, and maintaining the balance between excitation and inhibition in the brain.