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Functional Hypogonadism Correction

Meaning

Functional Hypogonadism Correction refers to the clinical strategy of reversing a state of reduced gonadal hormone production, typically testosterone or estrogen, that is not due to intrinsic gonadal failure but rather to reversible suppression from external factors, often chronic stress, metabolic dysfunction, or excessive exercise. The correction involves identifying and mitigating the underlying systemic stressors that suppress the hypothalamic-pituitary-gonadal (HPG) axis. This approach aims to restore endogenous hormone production, which is often preferred over exogenous hormone replacement therapy.