The holistic study of human physiology focused not merely on the structure of systems but on their dynamic, interactive performance capabilities under various internal and external stressors. It emphasizes the integrated network of endocrine, metabolic, and neurological functions working in concert. We are interested in how well the body works, not just how it is built.
Origin
This term is a product of the integrative medicine movement, which critiques the reductionist approach by demanding an understanding of interconnected biological systems. It signifies a practical application of physiological knowledge toward achieving optimal operational capacity. The focus is inherently systems-oriented.
Mechanism
The operational mechanism involves assessing the cross-talk between major regulatory axes, such as the gut-brain axis and the HPA axis, to identify points of systemic friction. Interventions aim to restore appropriate signal transduction fidelity across these interfaces. By ensuring harmonious communication between organ systems, overall physiological output is enhanced.
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