What is the Origin of Functional Healthspan Extension?

This term is a synthesis of gerontology principles with an emphasis on functional capacity, often influenced by research into hormonal optimization and cellular health. The "extension" implies an active intervention to push back the onset of age-related functional decline. It directly relates to the clinical objective of maintaining autonomy and vigor.

What is the Mechanism of Functional Healthspan Extension?

Extension is achieved by mitigating key drivers of functional decline, such as chronic low-grade inflammation or progressive loss of anabolic signaling fidelity. Interventions might focus on maintaining optimal levels of key hormones that support muscle mass and neural integrity, like testosterone or thyroid hormones. This sustained physiological support delays sarcopenia and cognitive impairment.

Functional Healthspan Extension

Meaning

Functional Healthspan Extension is the targeted prolongation of the years lived with high levels of physical capability, cognitive sharpness, and robust endocrine regulation, independent of chronological age. This is distinct from merely extending lifespan; the goal is to compress morbidity. We aim to maintain physiological function near peak levels for a longer duration.