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Functional Euthyroidism

Meaning

Functional Euthyroidism describes a clinical state where a patient exhibits optimal thyroid hormone action at the cellular level, despite potentially having thyroid-stimulating hormone (TSH) and total thyroid hormone levels that fall within the statistically normal laboratory reference range. This state prioritizes the patient’s physiological well-being and the absence of hypothyroid symptoms over mere adherence to broad laboratory values. Achieving this functional balance requires careful consideration of free hormone levels and peripheral conversion efficiency.