Functional Decline Mitigation involves proactive clinical strategies aimed at slowing or partially reversing the age-associated deterioration of physiological capacities across multiple organ systems. This approach prioritizes maintaining performance metrics over simply managing chronic disease symptoms. We focus on preserving operational efficiency.
Origin
This concept is borrowed from longevity research and regenerative medicine, emphasizing a proactive stance against sarcopenia, immunosenescence, and metabolic drift associated with advancing years.
Mechanism
Mitigation is achieved by addressing the root causes of functional loss, often involving the optimization of anabolic signaling pathways, reduction of chronic systemic inflammation, and support for mitochondrial health. By improving cellular energy production and repair mechanisms, the overall functional reserve of the organism is preserved or enhanced.
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