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FTO Gene

Meaning

The FTO Gene, formally known as the Fat Mass and Obesity-associated gene, is a highly significant genetic locus strongly linked to an individual’s body mass index (BMI) and the physiological propensity for fat accumulation in human populations. Specific common single nucleotide polymorphisms (SNPs) within this gene, particularly the rs9939609 variant, are clinically associated with an increased statistical risk of obesity and metabolic syndrome. While not entirely deterministic, the presence of these alleles can significantly influence an individual’s metabolic efficiency and the regulation of satiety signals.