Free Testosterone Metrics

Meaning

Clinical measurements and analytical values that quantify the biologically active, unbound fraction of testosterone circulating in the bloodstream. This metric is considered a more accurate indicator of androgenic effect on target tissues compared to total testosterone, as only the free hormone can readily diffuse across cell membranes and interact with its receptors. These metrics are crucial for diagnosing functional androgen deficiency, regardless of total levels. Accurate assessment is essential for personalized hormonal intervention.

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HRTioSeptember 28, 2025