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Free Testosterone Assay Sensitivity

Meaning

Free Testosterone Assay Sensitivity refers to the lowest concentration of unbound, biologically active testosterone that a laboratory measurement technique can reliably and accurately detect. This metric is a critical performance characteristic of an assay, particularly when assessing individuals with low-normal or frankly low testosterone levels, where precision at the lower end of the reference range is essential for clinical decision-making. High sensitivity is necessary because free testosterone constitutes only a small fraction of total circulating testosterone.