What is the Origin of Free Radical Scavenging?

This concept derives directly from the field of biochemistry and the study of reactive oxygen species (ROS) pathology within living systems. It highlights the indispensable role played by both endogenous and exogenous antioxidants in maintaining cellular defense integrity against unstable molecules. The term clearly defines the active removal or deactivation process targeting these unstable chemical species.

What is the Mechanism of Free Radical Scavenging?

Scavenging involves the precise donation of an electron or a hydrogen atom from an antioxidant molecule, such as glutathione or various lipid-soluble vitamins, to the free radical, stabilizing it into a harmless, non-reactive product. This action effectively interrupts the propagation of damaging processes like lipid peroxidation, protein carbonylation, and DNA adduct formation. Maintaining high levels of endogenous enzymatic scavengers, such as Superoxide Dismutase, is critical for robust systemic defense.

Free Radical Scavenging

Meaning

Free Radical Scavenging is the essential biochemical process wherein specialized molecules neutralize highly reactive species, known as free radicals, thereby preventing them from initiating damaging chain reactions within cellular components. This function is fundamental to mitigating oxidative stress, a major contributor to cellular aging and systemic hormonal dysfunction. Effective scavenging preserves the structural integrity of all tissues, including sensitive endocrine cells.