Skip to main content

Free Hormone Optimization

Meaning

Free Hormone Optimization is the clinical process dedicated to maximizing the concentration of unbound, biologically active steroid hormones available for cellular receptor interaction, while maintaining overall endocrine system stability. This optimization targets the free fractions of hormones like testosterone, estrogen, and DHEA, recognizing that these are the moieties that drive physiological effect at the tissue level. Achieving this balance supports vitality, mood, and physical function without inducing supra-physiological total hormone states.