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Free Hormone Assessment

Meaning

Free hormone assessment is a specialized diagnostic laboratory procedure that precisely measures the concentration of biologically active, unbound hormones circulating in the bloodstream. Unlike total hormone measurements, which quantify both protein-bound and free fractions, this assessment provides a more accurate reflection of the hormone available to engage with target tissue receptors and elicit a biological effect. Clinically, it is considered a superior metric for determining true hormonal status and the resulting tissue impact, especially for potent steroid and thyroid hormones.