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Free Fatty Acid Modulation

Meaning

Free Fatty Acid Modulation refers to the targeted physiological or pharmacological control over the concentration, release, and utilization of non-esterified fatty acids (NEFAs) within the circulation. This is a critical component of metabolic health, as NEFAs serve as a primary energy substrate for many tissues and their dysregulation is linked to insulin resistance and lipotoxicity. Effective modulation aims to maintain a healthy balance between lipolysis and fatty acid oxidation.