What is the Origin of Framingham Risk Score?

The score originated from the Framingham Heart Study, a landmark, long-term, ongoing epidemiological cohort study initiated in 1948 in Framingham, Massachusetts. This study was instrumental in identifying the major risk factors for cardiovascular disease in the general population. The resulting algorithm, developed from decades of longitudinal data, became a standardized clinical tool for risk stratification.

What is the Mechanism of Framingham Risk Score?

The calculation mechanism assigns specific point values to various cardiovascular risk factors, with higher points correlating to a greater predicted probability of a major cardiac event within the next decade. Hormonal health significantly intersects with this score, as dyslipidemia and hypertension, key inputs to the algorithm, are often modulated by endocrine status, including thyroid function and sex hormone balance. By quantifying cumulative risk, the score helps clinicians and patients prioritize lifestyle and pharmaceutical interventions to mitigate future vascular pathology.

Framingham Risk Score ∞ Area

Framingham Risk Score

Meaning

The Framingham Risk Score is a validated, gender-specific algorithm utilized in clinical practice to estimate an individual’s 10-year risk of developing general cardiovascular disease, including coronary heart disease, stroke, and heart failure. This prognostic tool integrates key modifiable and non-modifiable risk factors, such as age, total cholesterol, HDL cholesterol, systolic blood pressure, smoking status, and diabetes history. It serves as a foundational metric for guiding preventative strategies and therapeutic interventions in cardiovascular health, directly impacting longevity planning.

A translucent, intricate helix wraps a wooden stick. This embodies the delicate endocrine system and precise hormonal optimization through Hormone Replacement Therapy. It signifies careful titration of bioidentical hormones like Testosterone Cypionate for homeostasis and metabolic health.

Can Progesterone Therapy Be Safely Initiated for Cardiovascular Support in Older Women?

Initiating micronized progesterone therapy in early postmenopause appears neutral to beneficial for cardiovascular health, supporting the system's recalibration.

∞ Framingham Risk Score
∞ Endothelial Function
∞ Oral Micronized Progesterone

HRTioAugust 1, 2025

Framingham Risk Score

Meaning

Origin

Mechanism

Can Progesterone Therapy Be Safely Initiated for Cardiovascular Support in Older Women?

Provided by the clinical team
at 4Ever Young Miami Dadeland

-15% ∞ HRTIO15

Your protocol begins with a conversation.

Visit

Schedule Appointment

About

Med & Wellness

4Ever Young Miami Dadeland

Communication

+1 786-529-6686

Email Us

Opening Hours