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Frailty Syndrome Mitigation

Meaning

Frailty Syndrome Mitigation is the clinical strategy aimed at actively preventing, slowing, or reversing the multi-system physiological decline characterized by reduced strength, endurance, physical activity, and unintentional weight loss. This comprehensive approach targets the underlying biological mechanisms of sarcopenia, immunosenescence, and neurodegeneration, which are often significantly exacerbated by age-related hormonal deficits. Successful mitigation enhances functional independence, reduces vulnerability to stressors, and dramatically improves quality of life in later years.