The initial, systematic clinical effort focused on establishing optimal circulating levels for the primary endocrine regulators, such as sex steroids, thyroid hormones, and cortisol, before addressing secondary or peripheral modulators. This involves comprehensive baseline testing and targeted restoration to the upper quartile of established reference ranges. We prioritize establishing a stable endocrine substrate for overall health.
Origin
This term blends the concept of a structural base (“foundation”) with targeted modification (“optimization”) within the realm of endocrine health management. It implies a hierarchical approach to hormonal intervention based on core axis stability.
Mechanism
The mechanism involves identifying the primary bottlenecks in the HPA, HPG, or HPT axes, often through measuring upstream pituitary signals and downstream end-organ feedback. Correcting these foundational imbalances permits downstream physiological systems to operate more efficiently without requiring complex ancillary support.
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