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Follicular Phase Signaling

Meaning

Follicular Phase Signaling refers to the intricate, precisely timed cascade of endocrine communication that characterizes the first half of the female menstrual cycle, spanning from the commencement of menstruation through to the critical moment of ovulation. This signaling sequence is defined by the pulsatile release of Gonadotropin-Releasing Hormone (GnRH), which subsequently stimulates the pituitary secretion of Follicle-Stimulating Hormone (FSH), culminating in ovarian follicle growth and a progressive, steady rise in estradiol production. The integrity of this entire communication process is absolutely essential for both reproductive health and systemic hormonal balance.