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Fludrocortisone Replacement

Meaning

Fludrocortisone Replacement is a specific pharmacologic intervention used to substitute for deficient mineralocorticoid activity, primarily in patients diagnosed with primary adrenal insufficiency or congenital adrenal hyperplasia. Fludrocortisone acetate, a potent synthetic mineralocorticoid, is administered to restore electrolyte and fluid balance, crucial for maintaining blood pressure and preventing volume depletion. This treatment is a cornerstone for managing the salt-wasting component of these adrenal disorders.