Skip to main content

Finasteride Pharmacokinetics

Meaning

Finasteride pharmacokinetics is the quantitative description of the absorption, distribution, metabolism, and excretion (ADME) of the drug finasteride within the human body. Finasteride is a selective inhibitor of the Type 2 isoform of 5-alpha reductase, the enzyme that converts testosterone into dihydrotestosterone (DHT). Key pharmacokinetic parameters include its good oral absorption, extensive metabolism in the liver via the CYP3A4 enzyme, and a relatively short elimination half-life, which typically necessitates once-daily dosing to maintain therapeutic efficacy. Understanding this profile is essential for managing its clinical effects and predicting drug interactions.