What is the Origin of Fibrous Capsule?

The term originates from classical anatomy and histology, combining 'fibrous,' indicating a composition of fibers, and 'capsule,' from the Latin 'capsula' meaning "a small box or container." Its function as a tough, enclosing membrane was recognized early in anatomical studies. In clinical practice, the term gained specific relevance with the advent of implantable medical devices, where the body's natural healing response creates a fibrous capsule around the foreign material.

What is the Mechanism of Fibrous Capsule?

The biological mechanism of a fibrous capsule is twofold: protection and containment. For native organs, it provides mechanical stability and limits expansion. In the case of a subcutaneous hormone implant, the formation of a capsule is a normal foreign body reaction orchestrated by the immune system. This capsule acts as a diffusion barrier, regulating the rate at which the hormone is released from the implant's matrix into the systemic circulation, thereby influencing the therapy's long-term pharmacokinetic profile.

Fibrous Capsule ∞ Area

Fibrous Capsule

Meaning

A Fibrous Capsule is a dense layer of connective tissue, composed primarily of tough, inelastic collagen fibers, that envelops and structurally supports various organs, joints, and certain medical implants within the body. This sheath provides physical protection, helps maintain the organ’s shape and position, and delineates boundaries within anatomical structures. In the context of hormonal health, it can refer to the protective layer around glands like the adrenal cortex or the reactive tissue forming around a subcutaneous hormone implant.