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Fibroblasts

Meaning

Fibroblasts are the most common cell type found in connective tissue, serving as the principal structural cells responsible for synthesizing the extracellular matrix (ECM) and collagen. These cells are crucial for maintaining the structural integrity and mechanical properties of tissues, including the dermis of the skin, tendons, and ligaments. In the context of hormonal health and longevity, their function is particularly relevant to skin elasticity and wound healing, both of which are significantly influenced by circulating hormone levels, such as estrogen and testosterone. Their decline in function with age is a key contributor to tissue senescence.