A holistic, integrated approach encompassing lifestyle, nutritional, and pharmacological interventions specifically designed to manage the fluctuating hormonal symptoms and long-term health risks associated with the perimenopausal transition in women. This period is characterized by erratic ovarian function leading up to the final menstrual period.
Origin
The phrase is descriptive, combining ‘female,’ ‘perimenopause’ (from Greek peri- meaning around, and ‘menopause’ meaning cessation of menstruation), and ‘support,’ indicating assistance or comprehensive management. It addresses the unique clinical needs during the years preceding the established menopausal state.
Mechanism
Support mechanisms focus on stabilizing the hypothalamic-pituitary-ovarian (HPO) axis fluctuations, particularly managing the effects of declining and erratic estrogen and progesterone levels on target tissues. Interventions may include targeted nutrient supplementation to support neurotransmitter balance and bone health, as well as bioidentical hormone replacement therapy to alleviate acute vasomotor symptoms and protect against accelerated bone density loss and adverse cardiovascular changes. The primary goal is to smooth the transition and mitigate associated quality-of-life and longevity concerns.
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