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Female Metabolic Dysfunction

Meaning

Female Metabolic Dysfunction describes a specific and complex cluster of physiological abnormalities in women, characterized by significant derangements in glucose homeostasis, unfavorable lipid profiles, elevated blood pressure, and an accumulation of visceral adipose tissue. This condition is frequently exacerbated by natural shifts in sex hormone levels, such as those occurring during Polycystic Ovary Syndrome (PCOS), perimenopause, or the post-menopausal state, where the decline in protective estrogen can profoundly impair insulin sensitivity. The clinical presentation substantially increases the long-term risk for serious health sequelae, including accelerated cardiovascular disease, the onset of type 2 diabetes, and non-alcoholic fatty liver disease. Effective clinical management mandates a holistic, multi-faceted approach addressing hormonal, nutritional, and lifestyle factors to successfully restore systemic metabolic homeostasis.