Female Hormonal Cycling refers to the precisely orchestrated, repeating sequence of physiological events driven by fluctuating levels of ovarian steroids and pituitary gonadotropins, primarily the menstrual cycle. This complex interplay regulates reproductive function, but also profoundly impacts mood, energy metabolism, and bone density maintenance. Understanding these cycles is central to assessing overall endocrine health in women.
Origin
The term is rooted in reproductive endocrinology, stemming from observations of cyclical changes in the female reproductive system over approximately 28 days. The “cycling” aspect emphasizes the dynamic, non-steady-state nature of hormone secretion controlled by the hypothalamic-pituitary-ovarian (HPO) axis.
Mechanism
The mechanism involves pulsatile release of Gonadotropin-Releasing Hormone (GnRH) from the hypothalamus, stimulating the pituitary to release Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH). These gonadotropins drive follicular development and subsequent estrogen and progesterone production by the ovaries, which in turn feedback to regulate the HPO axis itself. This negative and positive feedback loop ensures cyclical preparation for potential conception.
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