Female Biology encompasses the unique constellation of endocrine cycles, reproductive physiology, and associated metabolic patterns characteristic of the female human system. Central to this is the cyclical regulation by ovarian hormones, primarily estrogen and progesterone, influencing nearly every tissue type. A nuanced understanding is essential for precision health.
Origin
This term reflects the historical differentiation of physiological study based on sex differences, evolving from reproductive focus to recognizing systemic hormonal influences across the lifespan. It acknowledges inherent biological variance between sexes.
Mechanism
The primary mechanism involves the hypothalamic-pituitary-ovarian (HPO) axis driving the menstrual cycle, which dictates fluctuating levels of sex steroids. These steroids exert pleiotropic effects, modulating everything from bone density and lipid metabolism to mood regulation via specific nuclear receptor interactions.
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