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Fc Fusion

Meaning

Fc Fusion is a sophisticated protein engineering technique where a therapeutic peptide or protein, such as a growth factor or hormone analog, is genetically fused to the Fc (Fragment crystallizable) region of an immunoglobulin G antibody. This molecular modification is specifically designed to enhance the pharmacological properties of the therapeutic agent. The resulting fusion protein exhibits a significantly prolonged half-life in circulation, which is a major advantage for chronic therapies.