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Fat-Soluble Hormone Derivation

Meaning

Fat-Soluble Hormone Derivation describes the biogenetic pathway where lipid-soluble hormones, specifically the entire class of steroid hormones and thyroid hormones, are chemically synthesized from their lipid or amino acid precursors. Steroid hormones, including cortisol, estrogen, and testosterone, are derived from cholesterol, a lipid molecule. Thyroid hormones, while structurally different, are also lipophilic and derived from the amino acid tyrosine and iodine. This commonality in lipid solubility dictates their transport mechanisms and their ability to cross cell membranes to act on intracellular receptors.