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Fat Oxidation Hormones

Meaning

Fat Oxidation Hormones are a group of endocrine signaling molecules that play a direct and regulatory role in stimulating lipolysis, the breakdown of stored triglycerides into free fatty acids, and promoting their subsequent utilization for energy production, a process known as beta-oxidation. Key hormones in this category include epinephrine, norepinephrine, glucagon, and certain peptides, which collectively mobilize fat reserves to meet the body’s energy demands, particularly during periods of fasting or exercise. Clinically, optimizing the action and signaling of these hormones is central to improving body composition and metabolic flexibility, ensuring the efficient use of fat as fuel.