Fasting Window Integrity refers to the strict and consistent maintenance of a period of zero caloric intake, typically lasting twelve or more hours, within a time-restricted feeding protocol. Maintaining this integrity is crucial because the fasting state initiates key metabolic switches, including the transition from glucose oxidation to fat oxidation and the activation of cellular repair pathways. Breaching this window with even minimal calories compromises the intended physiological effects.
Origin
This term originates directly from the clinical application and research of intermittent fasting and time-restricted eating protocols, emphasizing the critical importance of the non-feeding phase. The word integrity highlights the all-or-nothing nature of the biochemical state required to achieve the full benefits of fasting.
Mechanism
High integrity ensures a sustained reduction in circulating insulin, which is the primary hormonal signal that suppresses lipolysis and autophagy. A prolonged, uninterrupted fast allows for a significant rise in glucagon and growth hormone, promoting the breakdown of stored triglycerides and the clearance of damaged cellular material. This hormonal environment is essential for improving insulin sensitivity and mitochondrial health.
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