Fasting Protocols refer to structured, intentional patterns of voluntarily abstaining from food and, sometimes, caloric beverages for specific periods. These protocols, which include intermittent fasting and prolonged fasting, are utilized as metabolic strategies to induce beneficial physiological shifts. Clinically, they are employed to improve insulin sensitivity, promote cellular autophagy, and modulate hormonal pathways related to metabolism and longevity. Implementation requires careful consideration of individual health status and nutritional needs.
Origin
The concept of fasting is ancient, rooted in religious and cultural practices across many civilizations. The modern clinical term “Fasting Protocols” emerged from contemporary nutritional and longevity science, where the practice was systematized and studied for its specific metabolic effects. “Protocol” signifies a formal, structured procedure for conducting an activity.
Mechanism
The primary mechanism of fasting protocols involves shifting the body from a glucose-based metabolism to a fat-based metabolism, a state known as ketosis. During the fasting window, depleted glycogen stores lead to reduced insulin levels, which in turn signals the body to break down stored fat for energy. This metabolic switch activates cellular repair processes, such as autophagy, and significantly enhances tissue sensitivity to insulin and other metabolic hormones upon refeeding.
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