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Fasting and Medication

Meaning

Fasting and Medication refers to the critical clinical consideration of how periods of intentional caloric restriction, such as intermittent or prolonged fasting, interact with the pharmacokinetics and pharmacodynamics of prescribed medications. This interaction is complex, potentially altering drug absorption, distribution, metabolism, and excretion, which can lead to either reduced therapeutic efficacy or increased risk of adverse effects, particularly with drugs affecting blood sugar or liver enzymes. Clinicians must carefully manage this interface to ensure patient safety and drug effectiveness.