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Extracellular Matrix Synthesis

Meaning

Extracellular Matrix Synthesis is the fundamental biological process by which cells, predominantly fibroblasts and chondrocytes, manufacture and organize the complex scaffold of macromolecules that surrounds and supports all cells and tissues. This intricate matrix, composed mainly of various types of collagen, elastin, and specialized glycoproteins, is essential for maintaining tissue structure, providing mechanical strength, and mediating critical cell signaling. Maintaining robust synthesis is a key determinant of skin elasticity, joint integrity, and the overall capacity for tissue repair and regeneration.