A specific grade of olive oil obtained solely by mechanical or physical means, without chemical solvents, characterized by its low acidity and high content of monounsaturated fatty acids (MUFAs), predominantly oleic acid. The clinical significance lies in its rich profile of phenolic compounds, which possess potent antioxidant and anti-inflammatory properties crucial for cellular and vascular health. This oil is considered the highest quality for nutritional and therapeutic use.
Origin
The term is derived from the ancient practice of olive cultivation and oil extraction, with ‘Extra Virgin’ being a quality designation established by international standards based on chemical and organoleptic parameters. Its clinical application is deeply integrated into Mediterranean diet research and lipid metabolism studies.
Mechanism
The high oleic acid content supports cellular membrane fluidity and serves as a stable energy substrate, promoting optimal mitochondrial function. Crucially, the polyphenols, such as oleuropein and oleocanthal, exert their effects by modulating gene expression related to inflammation and oxidative stress. This action indirectly supports the stability of the endocrine system and maintains the integrity of the vascular endothelium.
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