External Output refers to the measurable, observable physiological or behavioral results that stem directly from the internal orchestration of the neuroendocrine system and cellular processes. In a clinical sense, this includes parameters like physical performance, basal metabolic rate, or measurable stress resilience, which serve as tangible indicators of underlying hormonal status. It is the manifestation of internal functional equilibrium.
Origin
This concept arises from systems analysis, differentiating between the internal regulatory machinery (the mechanism) and the externally verifiable results of that machinery’s operation. In physiology, it represents the functional expression of homeostasis being successfully defended or compromised.
Mechanism
The mechanism involves the final cascade where hormones bind to target tissues, initiating cellular physiology changes that manifest externally, such as increased thermogenesis or changes in muscular contractile efficiency. If the central command unit is signaling effectively, the external output will align with the body’s biological setpoints, reflecting optimal systemic performance.
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