What is the Origin of Extended Prime?

This term is not a standard medical diagnosis but rather a construct developed in the preventative and anti-aging medicine communities. It reflects a paradigm shift from treating disease to optimizing healthspan and maximizing the duration of functional youth. The concept builds upon the scientific understanding of hormesis and the plasticity of biological systems.

What is the Mechanism of Extended Prime?

Achieving an Extended Prime involves comprehensive lifestyle and clinical interventions aimed at preserving telomere length, enhancing mitochondrial efficiency, and modulating key longevity pathways like mTOR and AMPK. Hormonally, it focuses on maintaining youthful levels and ratios of critical steroid and peptide hormones, minimizing chronic low-grade inflammation, and ensuring high cellular insulin sensitivity.

Extended Prime

Meaning

Extended Prime is a conceptual term used within the longevity and wellness space to denote the prolonged maintenance of peak physiological and hormonal function well beyond the conventionally accepted age of reproductive or physical peak. This state is characterized by optimal endocrine balance, robust metabolic health, and sustained cognitive and physical vitality. The clinical objective is to mitigate age-related decline by actively managing the determinants of biological aging.