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Exogenous Signal Augmentation

Meaning

Exogenous Signal Augmentation is a therapeutic strategy in which external, non-naturally produced compounds or physical stimuli are intentionally introduced to amplify a specific, desired physiological response or signaling pathway within the body. This is distinct from simple replacement therapy, as the aim is to enhance the signal itself, often targeting receptors or secondary messenger systems to boost the body’s inherent function. Examples include using specific peptides or light therapy to increase endogenous hormone release or improve cellular communication. The clinical objective is to achieve a supra-homeostatic, beneficial effect that supports wellness or recovery.