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Exogenous Ketone Efficacy

Meaning

Exogenous Ketone Efficacy refers to the measured effectiveness of orally administered ketone bodies, such as beta-hydroxybutyrate (BHB) salts or esters, to reliably and significantly elevate circulating blood ketone levels independent of dietary carbohydrate restriction. This clinical metric assesses the compound’s ability to induce a state of nutritional ketosis quickly and predictably, bypassing the physiological processes of endogenous ketone production. The efficacy is evaluated based on the magnitude and duration of the resulting ketonemia and its subsequent impact on metabolic and cognitive parameters.