Exogenous Hormone Stabilization is the clinical strategy of managing external hormone administration to achieve stable, predictable physiological levels, minimizing fluctuations that drive receptor adaptation.
Origin
This practice is foundational in Hormone Replacement Therapy (HRT) and related endocrinological interventions, evolving from earlier, less consistent dosing schedules.
Mechanism
Stabilization is achieved through precise pharmacokinetics, often involving steady-state delivery systems or pharmacologically optimized dosing regimens that maintain circulating concentrations within a defined therapeutic window.
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