Skip to main content

Exogenous Hormone Cycling

Meaning

Exogenous Hormone Cycling is a clinical dosing strategy involving the intermittent administration of external (exogenous) hormones in a non-continuous pattern, specifically designed to mimic the body’s natural pulsatile or cyclical endocrine rhythms. This therapeutic approach is primarily utilized to prevent the suppression of the patient’s endogenous hormone production, which often occurs with continuous, high-dose replacement. By creating intentional breaks or variations in dosing, the practitioner aims to maintain receptor sensitivity and support the natural feedback loops of the hypothalamic-pituitary-gonadal (HPG) axis. It is a precise method for optimizing long-term hormonal health and minimizing dependency.